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News Items
May 2008
HealthDay Spotlights Prostate Cancer Research
HealthDay News reported May 1 on a study by Dr. Pinchas Cohen, a researcher at UCLA’s Jonsson Cancer Center and director of research and training in pediatric endocrinology at Mattel Children's Hospital UCLA. His research highlighted the difficulties involved in blocking the activity of insulin-like growth factor in order to treat prostate cancer. The report also appeared on the web sites for Forbes and U.S. News & World Report, among others.“Complications Found in Proposed Prostate Cancer Treatment”
http://www.washingtonpost.com/wp-dyn/content/article/2008/05/01/AR2008050101686.htmlA May 15th article featured in the Prostate Cancer Foundation’s newsletter reports that eating less polyunsaturated fat can help prevent prostate cancer in mice. The senior author of the article is Dr. William Aronson, professor of urology and a researcher at the Jonsson Cancer Center at UCLA.
"Lowering Dietary Fat May Help Prevent Prostate Cancer"
http://www.prostatecancerfoundation.org/site/c.itIWK2OSG/b.4148383/k.EE29
/Lowering_Dietary_Fat_May_Help_Prevent_Prostate_Cancer.htm?msource=may08np&auid=3691977
Urology Trade Features Prostate Cancer Study
The May 6 issue of Renal & Urology News highlights a study on the spread of prostate cancer conducted by Dr. Robert Reiter, a professor of urology and a researcher at UCLA’s Jonsson Cancer Center. The research appeared in Cancer Research.“Clue to Prostate Cancer Spread Found”
http://www.renalandurologynews.com/Clue-to-Prostate-Cancer-Spread-Found/article/109794/
March 2008
Trade Publications Feature Prostate Cancer Study
A study finding that hormone-refractory prostate cancers are more likely to spread than hormone-dependent cancers was cited in the March 21 issues of the trade publications Drug Week, Biotech Business Week, Oncology Business Week, Preventive Medicine Week, Law & Health Weekly, MD Week, Heath & Medicine Week and Biotech Law Weekly. The study was led by Dr. Robert Reiter, a professor of urology and a researcher at UCLA’s Jonsson Cancer Center.
February 2008
February 22, 2008
Prostate Cancer Study Featured by Web News Site
A study which found that hormone refractory prostate cancers are more likely to spread than hormone dependent cancers was featured Feb. 22 by HealthOrbit.com. The study was led by Dr. Robert Reiter, a professor of urology and a researcher at UCLA’s Jonsson Cancer Center.
"Androgen Independent Prostate Cancers More Likely To Spread Than”
http://healthorbit.ca/NewsDetail.asp?opt=1&nltid=035190208
August 2006
News Items
August 4, 2006
Diet’s Effect on Prostate Cancer Draws Wide Coverage
Health Day News and Ivanhoe reported Aug. 1, and Reuters Health and United Press International reported Aug. 2 on new animal research showing that altering the typical Western diet to include more omega-3 fatty acids and less omega-6 fatty acids may reduce prostate tumor growth rates and PSA levels. The study was published Aug. 1 in Clinical Cancer Research. Dr. William Aronson, professor of urology and a researcher with the Jonsson Cancer Center, was quoted. The Health Day report also appeared in Forbes.com, CBC News.com (Canada), PhysOrg.com, Health Central.com and Food Consumer.com. The Reuters Health story was picked up by Health Sentinel.com, Gulf News.com, Trade Arabia.com and Cancer Page.com. Other Web coverage included eMaxHealth, Health24, Food Navigator, Best Syndication, News Target (Taiwan) and MedIndia.
"Dietary Changes May Slow Prostate Cancer Growth”
http://today.reuters.co.uk/news/newsArticle.aspx?type=healthNews&storyID=2006-08-02T015813Z_01_HUN207044_RTRIDST_0_HEALTH-DIETARY-DC.XML
"Altering Fatty Acid Intake May Help Fight Prostate Cancer”
http://www.healthday.com/view.cfm?id=534110
"More Omega-3 May Help Cut Prostate Cancer”
http://www.upi.com/ConsumerHealthDaily/view.php?StoryID=20060801-031921-5589r
"Balancing Fats May Help Prostate Cancer”
http://www.ivanhoe.com/channels/p_channelstory.cfm?storyid=14236
July 2005
News ItemsMay 18, 2005
Low Fat Diet Slows Growth of Prostate Cancer Cells
"Blood from men who had undergone the low-fat group significantly reduced in vitro growth of LNCaP cells compared to Western diet serum."May 18, 2005 - A high-fat diet and sedentary lifestyle may predispose men to develop prostate cancer through changes in serum hormones and growth factors. In a previous study, researchers from University of California, Los Angeles and Baltimpor, MA. showed that blood drawn from men who were limited to a low-fat diet and were exercising reduced serum-stimulated growth of prostate cancer cells ina dish. At the American Urological Association annual meeting this past May, the same research team presented results of another study they designed to see whether a low-fat vs Western diet affects the blood supply's impact on prostate cancer growth. This study involved men with prostate cancer on watchful waiting. They took 18 men with prostate cancer and randomized them to eat either a low-fat (15% calories from fat) or a regular Western (40% calories from fat) diet for 4-weeks. The men's fasting blood was drawn before and after the diet period, and measured for sex hormones, lipids, fatty acids, IGF-I and IGF binding proteins.To make sure the men stuck to the assigned diet, all their meals were prepared at the UCLA Clinical Research Center, with close monitoring by a research dietician. To assess the effect of the diet on prostate cancer growth, LNCaP cells were cultured in the laboratory and bathed in "before" and "after" serum drawn from these 2 groups of 9 men each. RESULTSBlood from men who had undergone the low-fat group significantly reduced in vitro growth of LNCaP cells compared to Western diet serum. Serum levels of linoleic acid (omega-6, the predominant fatty acid in the Western diet in baked and fried food) were significantly reduced in the low-fat relative to the Western diet group and positively correlated with serum-stimulated growth. In addition, serum omega-3 fatty acid levels (found in fish oil, predominant in the Asian diet) negatively correlated with serum-stimulated growth. There was a trend for serum IGFBP-1 levels to negatively correlate with serum-stimulated growth in the low-fat group. CONCLUSIONSIn this prospective randomized dietary intervention trial, a low-fat diet resulted in changes in serum fatty acid levels that impacted the growth of human LNCaP cancer cells in a dish.Further studies are indicated evaluating reducing linoleic acid intake and increasing omega-3 fatty acid intake for prostate cancer prevention and treatment.GROWTH INHIBITORY EFFECTS OF A LOW-FAT DIET ON PROSTATE CANCER CELLS IN VITRO: RESULTS OF A PROSPECTIVE RANDOMIZED DIETARY INTERVENTION TRIAL IN MEN WITH PROSTATE CANCER
William J Aronson*, Los Angeles, CA; Stephen J Freedland, Baltimore, MD; Francisco Conde, Naoko Kobayashi, Pinchas Cohen, Tung Ngo, Pak Leung, Susan Bowerman, Jenny Hong, Brandon Varr, Patricia deMiranda, David Elashoff, John Glaspy, Susanne Henning, David Heber, R James Barnard, Los Angeles, CA. Abstract This page reported by J. Strax, last updated May 18, 2005
For other news about Prostate Cancer:
http://psa-rising.com/med/info/lowfat.htm